Oral and Dental Diseases: Ac45 silencing mediated by AAV-sh-Ac45-RNAi prevents both bone loss and inflammation caused by periodontitis C1 Silencing Attenuates Inflammation and Alveolar Bone Resorption in Endodontic Disease The Triple Functions of D2 Silencing in Treatment of Periapical Disease The silencing of cathepsin K used in gene therapy for periodontal disease reveals the role of cathepsin K in chronic infection and inflammation